Sepsis treatment
Prophylactic treatment: treatment of wounds and diseases valve, complete drainage of any septic focus.
Cure: in intensive care service, conducted by an interdisciplinary team: Reanimator - ATI-st, surgeon, , internist, cardiologist, neurologist, etc.).
Medical treatment consists of:
- Broad spectrum antibiotics endovenous in high doses (possibly anti-fungal)
- Associated with functional and metabolic imbalances (fresh blood transfusion, and crystalloid infusion of colloidal solution, anabolic vitamins)
- Increase the body's nonspecific resistance.
- Pathogenic medication (corticosteroids - to protect cell membranes in toxic-septic shock, heparin therapy - for prevention of disseminated intravascular coagulation, hyperbaric oxygen, specific immune sera)
- Symptomatic medications (analgesics, antipyretics, etc.).
Surgery
The detection of infectious centre will require exhaust and local drainage (pleural abscess, peritoneal, subhepatic, right iliac fossa, etc).
Sepsis causes cardiopulmonary complications as a result of disruption of gas exchange in the lungs and decrease oxygen in arterial blood pressure. The adult respiratory distress syndrome installs. It produces an abnormal distribution of arterial blood flow to various organs and tissues in the body.
If no prompt intervention is applied, the patient may die. The doctor combats infection, to ensure hemodynamic and ventilatory support. Targeted antimicrobial therapy is based on the results hemoculture and sensitivity. Until the results of culture, an empirical antimicrobial therapy will begin, effective against both gram-positive and gram-negative. Therapy will take at least 7 days, depending on the particular disease.
To combat hypotension 1-2 liters of saline solution will be administrated intravenously, within 1-2 hours.
Patient intubation is often necessary to ensure optimal intake of oxygen. If hemoglobin concentration is low blood transfusion can be performed. An increased intake of calories for patients with sepsis can reduce the effects of protein hipercatabolism.
Prognosis and prevention
Almost half of patients in septic shock die within the first month. The risk of death is highly dependent on underlying disease and age of the patient, as well as physiological parameters of the body.
Sepsis can be prevented, thereby reducing mortality. Many cases of sepsis occur as a result of nosocomial complications (infections occurring as a result of medical maneuvers).
Therefore it is necessary to reduce risk maneuvers (catheterization, invasive surgical procedures).
In conclusion, it is absolutely necessary to combat quickly and efficiently the onset of sepsis, thus preventing organ dysfunction installation and hypotension.
Treatment of patients with septic shock consists of:
-Resuscitation of septic shock by correcting hypoxia, hypotension and oxygenation faulty
-Identify the source of infection and antimicrobial treatment, surgery
-Maintaining adequate organ function guided by cardiovascular monitoring and multiorgan dysfunction pathogenesis interruption.
Intravascular resuscitation:
All patients with sepsis require additional fluids. For adults crystalloid solution is administered. May be required a total of 4-6 liters. The patient will be monitored for signs of volume overload: dyspnoea, lung and pulmonary edema.
When resuscitation fails to stabilize the fluidic tissue perfusion pressor therapy is initiated. These agents are dopamine, norepinephrine, epinephrine and fenilefrina. These vasoconstrictors maintain adequate cardiac output voltage.
Prognosis:
Approximately 20-30% of patients with severe sepsis and 40% of those with septic shock die shortly after the infection is installed.
Sepsis treatment
Prophylactic treatment: treatment of wounds and diseases valve, complete drainage of any septic focus.
Cure: in intensive care service, conducted by an interdisciplinary team: Reanimator - ATI-st, surgeon, , internist, cardiologist, neurologist, etc.).
Medical treatment consists of:
- Broad spectrum antibiotics endovenous in high doses (possibly anti-fungal)
- Associated with functional and metabolic imbalances (fresh blood transfusion, and crystalloid infusion of colloidal solution, anabolic vitamins)
- Increase the body's nonspecific resistance.
- Pathogenic medication (corticosteroids - to protect cell membranes in toxic-septic shock, heparin therapy - for prevention of disseminated intravascular coagulation, hyperbaric oxygen, specific immune sera)
- Symptomatic medications (analgesics, antipyretics, etc.).
Surgery
The detection of infectious centre will require exhaust and local drainage (pleural abscess, peritoneal, subhepatic, right iliac fossa, etc).
Sepsis causes cardiopulmonary complications as a result of disruption of gas exchange in the lungs and decrease oxygen in arterial blood pressure. The adult respiratory distress syndrome installs. It produces an abnormal distribution of arterial blood flow to various organs and tissues in the body.
If no prompt intervention is applied, the patient may die. The doctor combats infection, to ensure hemodynamic and ventilatory support. Targeted antimicrobial therapy is based on the results hemoculture and sensitivity. Until the results of culture, an empirical antimicrobial therapy will begin, effective against both gram-positive and gram-negative. Therapy will take at least 7 days, depending on the particular disease.
To combat hypotension 1-2 liters of saline solution will be administrated intravenously, within 1-2 hours.
Patient intubation is often necessary to ensure optimal intake of oxygen. If hemoglobin concentration is low blood transfusion can be performed. An increased intake of calories for patients with sepsis can reduce the effects of protein hipercatabolism.
Prognosis and prevention
Almost half of patients in septic shock die within the first month. The risk of death is highly dependent on underlying disease and age of the patient, as well as physiological parameters of the body.
Sepsis can be prevented, thereby reducing mortality. Many cases of sepsis occur as a result of nosocomial complications (infections occurring as a result of medical maneuvers).
Therefore it is necessary to reduce risk maneuvers (catheterization, invasive surgical procedures).
In conclusion, it is absolutely necessary to combat quickly and efficiently the onset of sepsis, thus preventing organ dysfunction installation and hypotension.
Treatment of patients with septic shock consists of:
-Resuscitation of septic shock by correcting hypoxia, hypotension and oxygenation faulty
-Identify the source of infection and antimicrobial treatment, surgery
-Maintaining adequate organ function guided by cardiovascular monitoring and multiorgan dysfunction pathogenesis interruption.
Intravascular resuscitation:
All patients with sepsis require additional fluids. For adults crystalloid solution is administered. May be required a total of 4-6 liters. The patient will be monitored for signs of volume overload: dyspnoea, lung and pulmonary edema.
When resuscitation fails to stabilize the fluidic tissue perfusion pressor therapy is initiated. These agents are dopamine, norepinephrine, epinephrine and fenilefrina. These vasoconstrictors maintain adequate cardiac output voltage.
Prognosis:
Approximately 20-30% of patients with severe sepsis and 40% of those with septic shock die shortly after the infection is installed.
